Redefining Cancer Immunotherapy
Our technology pioneers a new class of microbial medicines engineered to reshape the tumor microenvironment and strengthen the immune response to cancer.
Our lead platform, SPIKE, uses engineered bacteria to selectively target solid tumors, remodel the tumor microenvironment, and enhance immune-based treatments—with a focus on safety, precision, and performance.
Our Approach
SPIKE is a genetically engineered living therapeutic that has been modified for cancer killing. It homes to tumors and reshapes the tumor microenvironment (TME), reducing suppressive signals and enhancing immune recognition. This remodeling creates a favorable landscape for the immune system to attack and eliminate cancer cells.
Tumor-Targeted Delivery
Engineered to seek out and act within solid tumors, delivering therapeutic activity directly where it’s needed.
Safe By Design
Built with biological safeguards and engineered for stability, precision, and controlled activity.
Built to Enhance Existing Therapies
Designed to work alongside leading immune-based treatments and amplify their potential.
Immune System Activation
Designed to reshape the tumor microenvironment and trigger powerful, localized immune responses.
Connect With Our Team
Learn more about our technology, research, and opportunities to collaborate.